Tione Buranda, Ph.D.


Associate Professor

Email: TBuranda@salud.unm.edu
Lab Website: The Buranda Laboratory


  • Plasma membrane organization, signaling and cell adhesion.
  • Spatiotemporal aspects of signaling and internalization.
  • Virus-host cell interactions (attachment and entry, effects on signal transduction, identification of new molecular targets relevant to viral pathogenesis: new approaches to identify cellular changes relevant to pathophysiology).
  • Dysregulation of cell barrier function due to virus infection and trauma

Education and Certification Information

Postdoctoral Fellowship
NSF Center for Photoinduced Charge Transfer
University of Rochester
Rochester, NY

Physical Inorganic Chemistry
Wayne State University
Detroit, MI

University of Toledo
Toledo, OH

Chemistry and Physics
Augustana College
Rock Island, IL

Selected Publications:

  • Chatzipanagiotou S, Ioannidis A, Trikka-Graphakos E, Charalampaki N, Sereti C, Piccinini R, Higgins AM, Buranda T, Durvasula R, Hoogesteijn AL, Tegos GP and Rivas AL (2016) Detecting the Hidden Properties of Immunological Data and Predicting the Mortality Risks of Infectious Syndromes. Front. Immunol. 7:217. doi: 10.3389/fimmu.2016.00217

  • Agola JO, Sivalingam D, Cimino DF, Simons PC, Buranda T, Sklar LA, Wandinger-Ness A. Quantitative bead-based flow cytometry for assaying Rab7 GTPase interaction with the Rab-interacting lysosomal protein (RILP) effector protein. Methods Mol Biol. 2015;1298:331-54. doi: 10.1007/978-1-4939-2569-8_28. PMID:25800855

  • Bondu V, Schrader R, Gawinowicz MA, McGuire P, Lawrence DA, Hjelle B, Buranda T. Elevated cytokines, thrombin and PAI-1 in severe HCPS patients due to Sin Nombre virus. Viruses. 2015 Feb 10;7(2):559-89. doi: 10.3390/v7020559. PMID:25674766

  • Tione Buranda*, Soumik BasuRay, Scarlett Swanson, Jacob Agola, Virginie Bondu, and Angela Wandinger-Ness. Rapid parallel flow cytometry assays of active GTPases using effector beads. Anal. Biochem. http://dx.doi.org/10.1016/j.ab.2013.07.039

  • Lin Hong, S. Ray Kenney, Genevieve K. Philips, Denise Simpson, Chad E. Schroeder, Julica Noth, Elsa Romero, Scarlett Swanson, Anna Waller, J. Jacob Strouse, Mark Carter, Alexandre Chigaev, Oleg Ursu, Tudor Oprea, Brian Hjelle, Jennifer E. Golden, Jeffrey Aube, Laurie G. Hudson, Tione Buranda, Larry A. Sklar, and Angela Wandinger-Ness. Characterization of a Cdc42 GTPase Inhibitor and its Use as a Molecular Probe J. Biol. Chem. 2013, 288, 8531-8543

  • Jacob O. Agola, Zurab Surviladze, Tione Buranda, Oleg Ursu, Anna Waller, Jake Strouse, Tudor I. Oprea, Larry A. Sklar and Angela Wandinger-Ness. In vitro Characterization of Rab7 GTPase Inhibition by a Small Chemical Inhibitor ACS Chem Biology 7, 1095-1108, 2012.

  • Tudor I. Oprea, Julie E. Bauman Cristian G. Bologa, Tione Buranda, Alexandre Chigaev, Bruce S. Edwards, Jonathan W. Jarvik, Hattie D. Gresham, Mark K. Haynes, Brian Hjelle, Robert Hromas, Laurie Hudson, Debra A. Mackenzie, Carolyn Y. Muller, John C. Reed, Peter C. Simons, Yelena Smagley, Juan Strouse, Zurab Surviladze Todd Thompson, Oleg Ursu, Anna Waller, Angela Wandinger-Ness, Stuart S. Winter, Yang Wu, Susan M. Young, Richard S. Larson, Cheryl Willman and Larry A. Sklar (2011) Drug Repurposing from an Academic Perspective. Drug Discovery Today: Therapeutic Strategies. 2011, 8, 61-69.

  • Tione Buranda, Yang Wu, Dominique Perez, Stephen D Jett, Virginie Bondu-Hawkins, Chunyan Ye, Bruce Edwards, Pamela Hall, Richard S. Larson, Gabriel P. Lopez, Larry A. Sklar, and Brian Hjelle. Recognition of DAF and αvβ3 by inactivated Hantaviruses, towards the development of HTS flow cytometry assays. Anal. Biochem 2010, 402: 151-160.

  • Tione Buranda, Yang Wu, Dominique Perez, Alexandre Chigaev, and Larry Sklar. Real time partitioning of octadecyl rhodamine B into bead supported lipid bilayer membranes reveals quantitative differences in saturable binding sites in DOPC and 1:1:1 DOPC/SM/Cholesterol membranes. J. Phys. Chem. B. 2010, 114, 1336-1349.

  • Tione Buranda, Yang Wu, Larry A. Sklar Subsecond Analyses of GPCR ternary complex dynamics by rapid mix flow cytometry Meth. Enzymol. 2009; 461:227-47.

  • Samantha L. Schwartz, Mathewos Tessema, Tione Buranda, Olena Pylypenko, Alexey Rak, Peter C. Simons, Zurab Surviladze, Larry A. Sklar, Angela Wandinger-Ness Flow cytometry for real-time measurement of guanine nucleotide binding and exchange by Ras-like GTPases. Analytical Biochemistry, 2008; Volume 381, Pages 258-266.

  • Tione Buranda, Anna Waller, Yang Wu, Peter C. Simons, Sean Biggs, Eric R. Prossnitz, Larry A. Sklar (2007) Some mechanistic insights into GPCR activation from detergent solubilized ternary complexes on beads Adv. in Prot. Chem. 2007; v.74, p.95-135.

  • Wu Y, Campos S, Lopez GP, Ozbun M, Sklar LA and Buranda T. The development of quantum dot calibration beads and quantitative multicolor bioassays in flow cytometry and microscopy. Anal Biochem 2007; 364:180-192. 10. Chigaev A, Waller A, Buranda T and Sklar L. Regulation of Cell Adhesion by Affinity and Extension of α4β1-Integrin. J Immun 2007; 178, 6828-6839.

  • Ning Y, Buranda T and Hudson LG. Activated receptor induces integrin α2 internalization via caveolae/raft dependent pathway. J Biol Chem. 2007; 282(9):6380-6387.

  • Burns AR, Frankel DJ and Buranda T. Local Mobility in lipid domains of supported bilayers characterized by atomic force microscopy and fluorescence correlation spectroscopy. Biophys J 2005; 89:1081-1093.

Search PubMed:

Tione Buranda on PubMed