Diane S. Lidke, Ph.D.

photo of Diane Lidke


Vice Chair for Research

Email: DLidke@salud.unm.edu
Lab Website: The Lidke Laboratory


  • Molecular mechanisms of signal transduction
  • Quantitative fluorescence microscopy

Education and Certification Information

Biophysical Sciences and Medical Physics
University of Minnesota, Minneapolis

Nebraska Wesleyan University, Lincoln
Graduated with High Distinction

Selected Publications:

  • C.C. Valley, D.J. Arndt-Jovin, N. Karedla, M.P. Steinkamp, A. Chizhik, W.S. Hlavachk, B.S. Wilson, K.A. Lidke, D.S. Lidke. “Enhanced dimerization drives ligand-independent activity of mutant EGFR in lung cancer.” Molecular Biology of the Cell. 26: 4087-99 (2015)

  • M. Pryor, M.P. Steinkamp, A.M. Halasz , Y. Chen , S. Yang, M.S. Smith, G. Zahoransky-Kohalmi, M. Swift, X. Xu, D. Hanien, N. Volkmann, D.S. Lidke, J.S. Edwards and B.S. Wilson. “Orchestration of ErbB3 signaling through hetero and homo-interactions.” Molecular Biology of the Cell. 26: 4109-23 (2015)

  • A. Carroll-Portillo, J.L. Cannon, J. te Riet, A. Holmes, Y. Kawakami, T. Kawakami, A. Cambi, D.S. Lidke. “Mast cells and dendritic cells form synapses that facilitate antigen transfer for T cell activation.” Journal of Cell Biology. 210: 851-864 (2015)

  • C.C. Valley, Liu, D.S. Lidke, K.A. Lidke. "Sequential Superresolution Imaging of Multiple Targets Using a Single Fluorophore" PLoS ONE, v.10, p.e0123941 (2015)

  • J. Broeken, H. Johnson, D.S. Lidke, S. Liu, R.P.J. Nieuwenhuizen, S. Stalling, K.A. Lidke B. Rieger. "Resolution improvement by 3D particle averaging in localization microscopy" Methods and Applications in Fluorescence, 3: 014003 (2015)

  • O. Coban, L.C. Zanetti-Dominguez, D.R. Matthews, D.J. Rolfe, G. Weitsman, P.R. Barber, J. Barbeau, V. Devauges, F. Kampmeier, M. Winn, B. Vojnovic, P.J. Parker, K.A. Lidke, D.S. Lidke, S.M. Ameer-Beg, M.L. Martin-Fernandez, T. Ng. “Effect of phosphorylation on EGFR dimer stability probed by single-molecule dynamics and FRET/FLIM.” Biophysical Journal. 108: 1013-1026 (2015)

  • S.L. Schwartz, Q. Yan, C.A. Telmer, K.A. Lidke, M.P. Bruchez, D.S. Lidke. “Fluorogen-Activating Proteins Provide Tunable Labeling Densities for Tracking FcεRI Independent of IgE.” ACS Chemical Biology. 10:539-546 (2015)

  • M.P. Steinkamp, S.T. Low-Nam, S. Yang, K.A. Lidke, D.S. Lidke, B.S. Wilson. “ErbB3 is an active tyrosine kinase capable of homo- and hetero-interactions.” Molecular and Cellular Biology. 34:965-77 (2014)

  • C.C. Valley, K.A. Lidke, D.S. Lidke. “The Spatiotemporal Organization of ErbB Receptors: Insights from Microscopy.” An invited chapter for Signaling by Receptor Tyrosine Kinases. Cold Spring Harbor Perspectives in Biology. J Schlessinger and MA Lemmon, eds. pp. 179-192 (2014)

  • P.J. Cutler, M.D. Malik, S. Liu, J.M. Byars, D.S. Lidke and K.A. Lidke. “Multi-color quantum dot tracking using a high-speed hyperspectral line-scanning microscope.” PLoS One. 8: e64320 (2013)

  • M.M. Pryor, S.T. Low-Nam*, A.M. Halasz, D.S. Lidke, B.S. Wilson and J.S. Edwards. “Dynamic Transition States of ErbB1 Phosphorylation Predicted by Spatial Stochastic Modeling.” Biophysical Journal, 105:1533-1543 (2013)

  • Carroll-Portillo, Z. Surviladze, A. Cambi, D.S. Lidke, and B.S. Wilson. “Mast cell synapses and exosomes: membrane contacts for information exchange.” Frontiers in Immunology. 3:46 (2012)

Search PubMed:

Diane S. Lidke on PubMed