Bruce S. Edwards, Ph.D.

photo of Bruce Edwards

Research Professor Emeritus



  • Flow cytometry
  • Adhesion Biology
  • High Throughput Screening of Molecular Targets by Flow Cytometry
  • Flow Cytometry Automation Software and Hardware Development

Education and Certification Information

University of Colorado
Boulder, CO

Birmingham Southern College
Birmingham, AL

Selected Publications:

  • Edwards BS, Sklar LA. Flow Cytometry: Impact on Early Drug Discovery. J Biomol Screen. 2015 Jul;20(6):689-707. doi: 10.1177/1087057115578273. Epub 2015 Mar 24. Review. PMID:25805180

  • Strouse JJ, Ivnitski-Steele I, Khawaja HM, Perez D, Ricci J, Yao T, Weiner WS, Schroeder CE, Simpson DS, Maki BE, Li K, Golden JE, Foutz TD, Waller A, Evangelisti AM, Young SM, Chavez SE, Garcia MJ, Ursu O, Bologa CG, Carter MB, Salas VM, Gouveia K, Tegos GP, Oprea TI, Edwards BS, Aubé J, Larson RS, Sklar LA. Selective Inhibition of ATP-binding Cassette Sub-family G Member 2. J Biomol Screening, 437:77-87, 2013

  • Cushing KW, Piyasena ME, Carroll NJ, Maestas GC, López BA, Edwards BS, Graves SW, López GP. Elastomeric Negative Acoustic Contrast Particles for Affinity Capture Assays. Anal Chem 85:2208-15, 2013

  • Edwards BS, Zhu JS, Chen J, Carter MB, Thal DM, Tesmer JJ, Graves SW, Sklar LA. Cluster Cytometry for High Capacity Bioanalysis, Cytometry A, 2012 Mar 19. [Epub ahead of print].

  • Chen J, Young SM, Allen C, Seeber A, Péli-Gulli M-P, Panchaud N, Waller A, Ursu P, Yao T, Golden JE, Strouse JJ, Carter MB, Kang H, Bologa CG, Edwards BS, Peterson BR, Aubé J, Werner-Washburne M, Loewith RJ, De Virgilio C, Sklar LA. Identification of a small molecular inhibitor of yeast TORC1 using a flow cytometry based multiplex screen. ACS Chem Biol. 2012 Feb 1. [Epub ahead of print].

  • Oprea TI, Bauman JE, Bologa CG, Buranda T, Chigaev A, Edwards BS, Jarvik JW, Gresham HD, Haynes MK, Hjelle B, Hromas R, Hudson L, Mackenzie DA, Muller CY, Reed JC, Simons PC, Smagley Y, Strouse J, Surviladze Z, Thompson T, Ursu O, Waller A, Wandinger-Ness A, Winter SS, Wu Y, Young SM, Larson RS, Willman C, Sklar LA. Drug Repurposing from an Academic Perspective. Drug discovery today. Therapeutic strategies 8:61-69, 2011.

  • Simons PC, Young SM, Carter MB, Waller A, Zhai DY, Reed JC, Edwards BS, Sklar LA, Simultaneous in vitro Molecular Screening of Protein - Peptide Interactions by Flow Cytometry Using Six Bcl-2 Family Proteins as Examples. Nature Protocols 6:943-952, 2011.

  • Edwards BS, Young SM, Ivnitsky-Steele I, Ye RD, Prossnitz ER, Sklar LA. High-content screening: flow cytometry analysis. Methods Mol Biol. ;486:151-65, 2009.

  • Young SM, Bologa CM, Fara D, Bryant BjK, Strouse JJ, Arterburn JB, Ye RD, Oprea TI, Prossnitz E, Sklar LA, Edwards BS. Duplex High Throughput Flow Cytometry Screen Identifies Two Novel Formylpeptide Receptor Family Probes. Cytometry 75A, 253-263, 2009.

  • Edwards BS, Young, S. M., Oprea, T. I., Bologa, C., Prossnitz, E., and Sklar, L. A. Biomolecular screening of formylpeptide receptor ligands with a sensitive, quantitative, high-throughput flow cytometry platform. Nature Protocols, 1:59-66, 2006.

  • Edwards BS, Bologa, C., Young, S. M., Balakin, K. V., Prossnitz, E., Savchuck, N. P., Sklar, L. A., and Oprea, T. I. Integration of virtual screening with high throughput flow cytometry to identify novel small molecule formylpeptide receptor antagonists. Mol. Pharmacol. 68:1301-1310, 2005.

  • Edwards BS, Curry, M.S., Tsuji, H., Larson, R.S, Brown, D., and L.A. Sklar. Expression of P-selectin at low site density promotes selective recruitment of eosinophils over neutrophils. J. Immunology. 165:404-410, 2000.

  • Kuckuck, F.W., Edwards BS, Sklar, L.A. High throughput flow cytometry. Cytometry 44:83-90, 2001.

  • Edwards BS, F. Kuckuck, L.A. Sklar. Plug flow cytometry: an automated coupling device for rapid sequential flow cytometric sample analysis. Cytometry 37:156-159, 1999.

Search PubMed:

Bruce S. Edwards My Bibliography / My NCBI Collection