the cannon laboratory
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  • Fricke, M., Letendre, K., Moses, M.E., Cannon, J.L. 2016. Persistence and adaptation in immunity: T cells balance the extent and thoroughness of search. PLoS Computational Biology. Mar 18;12(3):e1004818. PMID: 26990103 PMCID: PMC4798282

  • Drew Levin, Stephanie Forrest, Soumya Banerjee, Candice Clay, Judy Cannon, Melanie Moses, Frederick Koster. 2016. A spatial model of the efficiency of T cell search in the influenza-infected lung. Journal of Theoretical Biology. Feb 23;398:52-63. doi: 10.1016/j.jtbi.2016.02.022. PMID: 26920246

  • Amanda Carroll-Portillo, Judy L. Cannon, Joost te Riet, Anna Holmes, Yuko Kawakami, Toshi Kawakami, Alessandra Cambi, Diane S. Lidke. 2015. Mast cells and dendritic cells form synapses that facilitate antigen transfer for T cell activation. Journal of Cell Biology, Aug 31;210(5):851-64.

  • Lentendre, K., Donnadieu, E., Moses, M.E., Cannon, J.L. 2015. Statistical methods to accurately analyze in vivo T cell motility data. PLoS One, May 14;10(5):e0126333. doi: 10.1371/journal.pone.0126333. PMID: 25973755 PMCID: PMC4431811

  • Wan, G., Pehlke, C., Pepermans, R., Cannon, J.L., Lidke, D., Rajput, A. 2015. The H1047R point mutation in p110 alpha changes the morphology of human colon HCT116 cancer cells. Cell Death Discovery 1, Article number: 15044.

  • Qiang Wu, Elizabeth Berry, Tiffany Lu, Bryan S. Clay, Tamson V. Moore, Caroline M. Ferreira, Jesse W. Williams, Jasmine Moreno, Judy L. Cannon, Anne I. Sperling, and Rebecca A. Shilling. ICOS-expressing Tregs Promote Resolution of CD8-mediated Lung Injury. PLoS One. 2013;8(8):e72955. PMID: 23967339

  • Jesse Williams, Douglas Yau, Nan Sethakorn, Jacob Kach, Eleanor Reed, Tamson Moore, Judy Cannon, Xiaohua Jin, Heming Xing, Anthony Muslin, Anne Sperling, and Nickolai Dulin. RGS3 controls T lymphocyte migration in a model of Th2-mediated airway inflammation. Am J Physiol Lung Cell Mol Physiol. 2013 Nov;305(10):L693-701. PMID: 24077945

  • Cannon J.L.*, Asperti-Boursin, F., Letendre, K., Brown, I.K., Korzekwa, K.E., Blaine, K. M. Oruganti, S.R., Sperling, A.I., Moses, M.E. PKCθ regulates T cell motility via Ezrin-Radixin-Moesin localization to the uropod. PLOS One. 2013 Nov 8;8(11):e78940. PMID: 24250818 *corresponding author.

  • Zhou HF, Yan H, Cannon JL, Springer LE, Green JM, Pham CT.CD43-Mediated IFN-γ Production by CD8+ T Cells Promotes Abdominal Aortic Aneurysm in Mice. J Immunol. 2013 May 15;190(10):5078-85. doi: 10.4049/jimmunol.1203228. Epub 2013 Apr 12. PMID: 23585675 [PubMed - in process].

  • Moore TV, Clay BS, Cannon JL, Histed A, Shilling RA, Sperling AI. ICOS Controls T Cell Migration to the Lungs via Down-Regulation of CCR7 and CD62L. Am J Respir Cell Mol Biol. 2011. Vol. 45, pp. 843-850, 2011. PMID: 21421907

  • Cannon, J.L.#, Mody, P.D., Blaine, K.M., Nelson, A.D., Sayles, L., Moore, T.V., Clay, B.S., Bandukwala, H.S., Dulin, N.O., Shilling, R.A., Sperling, A.I. CD43 interaction with ERM proteins regulates T cell trafficking and CD43 phosphorylation. Molecular Biology of the Cell, 2011. Apr;22(7):954-63. #corresponding author PMID: 21289089

  • Moore TV, Clay BS, Ferreira CM, Williams JW, Rogozinska M, Cannon JL, Shilling RA, Marzo AL, Sperling AI. Protective effector memory CD4 T cells depend on ICOS for survival. PLoS One. 2011 Feb 18;6(2):e16529. PMID: 2136474

  • Driessens, G., Zheng, Y., Locke, F., Cannon, J.L., Gounari, F., Gajewski, T.F. 2011. β-catenin inhibits T cell activation by selective interference with LAT-PLC-γ1 phosphorylation. Journal of Immunology, Jan 15;186(2):784-90. PMID: 21149602

  • Shaffer MH, Huang Y, Corbo E, Wu GF, Velez M, Choi JK, Saotome I, Cannon JL, McClatchey AI, Sperling AI, Maltzman JS, Oliver PM, Bhandoola A, Laufer TM, Burkhardt JK. 2010. Ezrin is highly expressed in early thymocytes, but dispensable for T cell development in mice. PLoS One. 2010 Aug 27;5(8). pii: e12404. PMID: 20806059

  • Clay BS, Shilling RA, Bandukwala HS, Moore TV, Cannon JL, Welcher AA, Weinstock JV, Sperling AI. 2009. Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cells. PLoS One. Nov 4;4(11):e7525. PMID: 19888475

  • Shilling, R.A., Clay, B.S., Moore, T.V., Berry, E., Tesciuba, A.G., Bandukwala, H.S., Tong, J., Weinstock, J.V., Flavell, R.A., Horan, T., Yoshinaga S.K., Welcher, A.A., Cannon, J.L., Sperling, A.I. 2009. CD28 and ICOS play complementary non-overlapping roles in the development of Th2 immunity in vivo. Cellular Immunology, 2009;259(2):177-84. PMID: 19646680

  • Cannon, J.L. *#, Collins A. *, Balachandran D., Henriksen, K.J., Clay, B.S., Mody, P.D., Smith, C.E., Tong J., Miller S.D., Sperling A.I. 2008. CD43 regulates Th2 differentiation and inflammation. Journal of Immunology, 180: 7385-7393. *co-first authorship, #corresponding author. PMID: 18490738

  • Mody, P.D.*, Cannon, J.L.*, Bandukwala, H.S., Blaine, K.M., Schilling, A.B., Swier K., Sperling, A.I. 2007. Signaling through CD43 is required for CD4 T cell trafficking. Blood, Oct 15;110(8):2974-82. *co-first authorship. PMID: 17638845

  • Bandukwala, H.S., B.S. Clay, J. Tong, P.D. Mody, J.L. Cannon, R.A. Shilling, J.S. Verbeek, J.V. Weinstock, J. Solway, and A.I. Sperling. 2006. Signaling through FcγRIII is required for optimal Th2 responses and Th2-mediated airway inflammation. Journal of Experimental Medicine 204(8):1875-89. PMID: 17664287

  • Cannon, J.L., Burkhardt, J.K. Differential roles for WASP in actin regulation and IL2 production. 2004. Journal of Immunology 173(3):1658-62. PMID: 15265894

  • Zeng, R., Cannon, J.L., Abraham, R.T., Way, M., Billadeau, D.D., Bubeck-Wardenberg, J., Burkhardt, J.K. 2003. SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site. Journal of Immunology 171(3):1360-8. PMID: 12874226

  • Allenspach, E.J., P. Cullinan, J. Tong, Q. Tang, A.G. Tesciuba, J.L. Cannon, S.M. Takahashi, R. Morgan, J.K. Burkhardt, and A.I. Sperling. 2001. ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse. Immunity, 15:739-750. PMID: 11728336

  • Cannon, J.L., C. Case, G. Bosco, A. Seth, M. McGavin, K.A. Siminovitch, M.K. Rosen, and J.K. Burkhardt. 2001. WASP recruitment to the T cell-APC contact site occurs independently of Cdc42 Activation. Immunity 15:249-259. PMID: 11520460

  • Sedwick, C.E., M.M. Morgan, L. Jusino, J.L. Cannon, J. Miller and J.K. Burkhardt. 1999. TCR, LFA-1 and CD28 play unique and complementary roles in T cell cytoskeletal reorganization. Journal of Immunology 162:1367-1375. PMID: 9973391