Tracy I. George, M.D.

photo of Tracy George

Professor

Division Chief, Hematopathology

Director, Hematopathology Fellowship Program

Email: TracyGeorge@salud.unm.edu


Interests:

  • Translational hematopathology
  • Myeloproliferative neoplasms
  • Mastocytosis
  • Laboratory hematology
  • Reactive lymphadenopathies

Education and Certification Information

Fellowship:
Hematopathology Fellowship
Stanford University School of Medicine
Stanford, California
2000-2001

Surgical Pathology Fellowship
Stanford University School of Medicine
Stanford, California
1998-1999

Residency:
Pathology and Laboratory Medicine
University of California San Francisco School of Medicine
San Francisco, California
1995-1998
1999-2000

Chief Resident, Pathology
San Francisco General Hospital
San Francisco, California
1998

Chief Resident, Laboratory Medicine
University of California San Francisco School of Medicine
San Francisco, California
1999 and 2000

M.D.
University of California San Francisco School of Medicine
San Francisco, California
1995

Board Certifications:
Board certified hematology
American Board of Pathology (10/2001)

Board certified anatomic and clinical pathologist
American Board of Pathology (9/2000)

B.A.
Molecular Biology
University of California Berkeley
Berkeley, California
1990


Selected Publications:

  1. Gotlib J, Kluin-Nelemans HC, George TI, Akin C, Sotlar K, Hermine O, Awan FT, Hexner E, Mauro MJ, Sternberg DW, Villeneuve M, Huntsman Labed A, Stanek EJ, Hartmann K, Horny HP, Valent P, Reiter A. Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis. N Engl J Med. 2016 Jun 30;374(26):2530-41. doi: 10.1056/NEJMoa1513098. PMID:27355533

  2. Gars E, Yousry SM, Babu D, Kurzer JH, George TI, Gratzinger D. A replicable CD271+ mesenchymal stromal cell density score: bringing the dysfunctional myelodysplastic syndrome niche to the diagnostic laboratory. Leuk Lymphoma. 2016 Nov 3:1-3. [Epub ahead of print] No abstract available. PMID:27808583

  3. Steensma DP, Abedi M, Bejar R, Cogle CR, Foucar K, Garcia-Manero G, George TI, Grinblatt D, Komrokji R, Ma X, Maciejewski J, Pollyea DA, Savona MR, Scott B, Sekeres MA, Thompson MA, Swern AS, Nifenecker M, Sugrue MM, Erba H. Connect MDS/AML: design of the myelodysplastic syndromes and acute myeloid leukemia disease registry, a prospective observational cohort study. BMC Cancer. 2016 Aug 19;16:652. doi: 10.1186/s12885-016-2710-6. PMID:27538433

  4. Wang SA, Tam W, Tsai AG, Arber DA, Hasserjian RP, Geyer JT, George TI, Czuchlewski DR, Foucar K, Rogers HJ, Hsi ED, Bryan Rea B, Bagg A, Dal Cin P, Zhao C, Kelley TW, Verstovsek S, Bueso-Ramos C, Orazi A. Targeted next-generation sequencing identifies a subset of idiopathic hypereosinophilic syndrome with features similar to chronic eosinophilic leukemia, not otherwise specified. Mod Pathol. 2016 Aug;29(8):854-64. doi: 10.1038/modpathol.2016.75. PMID:27174585

  5. Ren M, Qin H, Wu Q, Savage NM, George TI, Cowell JK. Development of ZMYM2-FGFR1 driven AML in human CD34+ cells in immunocompromised mice. Int J Cancer. 2016 Aug 15;139(4):836-40. doi: 10.1002/ijc.30100. PMID:27005999

  6. CPM Hayward, KA Moffat, TI George, M Proytcheva, A Iorio. Report on the International Society for Laboratory Hematology survey on guidelines to support clinical hematology laboratory practice. International Journal of Laboratory Hematology 2016;38 Suppl 1:133-8.

  7. C Ustun, J Gotlib, U Popat, A Artz, B Scott, M Litzaow, A Reiter, R Nakamura, HC Kluin-Nelemans, S Verstovsek, A Pardanani, J Gajewski, M-A Perales, T George, T Shore, H Baurmann, W Sperr, W Saber, V Kota, S Yavuz, V Pullarkat, J Rogosh, K Van Besien, EP Alyea, H Haglung, K Sotlar, D Gandhi, O Hermine, M Arock, H-P Horny, DD Metcalfe, HJ Deeg, S Devine, D Weisdorf, C Akin, P Valent. Consensus opinion on allogeneic hematopoietic cell transplantation in advanced systemic mastocytosis. Biol Blood Bone Marrow Transplant 2016;22(8):1348-56.

  8. C Ustun, M Arock, HC Kulin-Nelemans, A Reiter, WR Sperr, T George, H-P Horny, K Hartmann, K Sotlar, G Damaj, O Hermine, S Verstovsek, DD Metcalfe, J Gotlib, C Akin, P Valent. Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice Haematologica 2016;101(10):1133-1143.

  9. D Chabot-Richards and TI George. White Blood Cell Counts: Reference Methodologies. In: Automated Cell Counters: State of the Art and New Directions. Clinics in Laboratory Medicine, C Brugnara, A Kratz (editors), Elsevier, Philadelphia, 35(1):11-24, 2015.

  10. K Hartmann, L Escribano, C Grattan, K Brockow, MC Carter, I Alvarez-Twose, A Matito, S Boresby-Olsen, F Siebenhaar, M Lange, M Niedoszytko, M Castells, JNG Oude Elberink, P Bonnadonna, R Zanotti, JL Hornick, A Torrelo, A Rabenhorst, B Nedoszytko, JH Butterfield, J Gotlib, A Reiter, D Radia, O Hermine, K Sotlar, TI George, TK Kristensen, HC Kluin-Nelemans, S Yavuz, H Hagglund, WR Sperr, LB Schwartz, M Triggiani, M Maurer, G Nilsson, H-P Horny, M Arock, A Orfao, DD Metcalfe, C Akin, P Valent. Cutaneous manifestations in mastocytosis: consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology. J Allergy Clin Immunol 2015 Oct 15. [Epub ahead of print]

  11. CPM Hayward, KA Moffat, TI George, M Proytcheva. Assembly and evaluation of an inventory of guidelines that are available to support clinical hematology laboratory practice. International Journal of Laboratory Hematology 2015, 37 (Suppl 1):36-45.

  12. AM Deucher, Z Qi, TI George, JE Etzell. BCL6 expression correlates with the t (1;19) translocation in B-cell lymphoblastic leukemia. Am J Clin Pathol 2015;143(4):547-57.

  13. KM Chisholm, JD Merker, JR Gotlib, G Gitana, M Lefterova, JL Zehnder, TI George, DA Arber, RS Ohgami. Mast cells in systemic mastocytosis have distinctly brighter CD45 expression by flow cytometry. Am J Clin Pathol 2015;143(4):527-34.

  14. AZ Mahmoud, TI George, DR Czuchlewski, QY Zhang, CS Wilson, CE Sever, AG Bakhirev, D Zhang, NL Steidler, KK Reichard, H Kang, K Foucar, MA Vasef. Scoring of MYC protein expression in diffuse large B-Cell lymphomas: concordance rate among hematopathologists. Modern Pathology 2014 Nov 28. [Epub ahead of print].

  15. RP Hasserjian, F Campigotto, V Klepeis, B Fu, SA Wang, C Bueso-Ramos, MJ Cascio, HJ Rogers, ED Hsi, C Soderquist, A Bagg, J Yan, RC Ochs, A Orazi, F Moore, A Mahmoud, TI George, K Foucar, J Oderm , C Booth, W Morice, DJ DeAngelo, D Steensma, RM Stone, D Neuberg, DA Arber. De novo acute myeloid leukemia with 20-29% blasts is less aggressive than acute myeloid leukemia with ≥30% blasts in older adults: a Bone Marrow Pathology Group study. Am J Hematol 2014; 89(11):E193-9. Epub 2014 July 31.

  16. D Chabot-Richards, TI George. Leukocytosis. International Journal of Laboratory Hematology 2014;36(3):279-88. Epub 2014 Apr 18. LS Ludwig, HT Gazda, JC Eng, SW Eichhorn, P Thiru, R Ghazvinia, TI George, JR Gotlib, AH Beggs, CA Sieff, HF Lodish, ES Lander, and VG Sankaran. Altered translation of GATA1 in Diamond-Blackfan anemia. Nature Medicine 2014;20(7):748-53. Epub 2014 Jun 22.

  17. P Valent, K Sotlar, WR. Sperr, L Escribano, S Yavuz, A Reiter, TI George, HC Kluin-Nelemans, O Hermine, J H Butterfield, H Hägglund, C Ustun, JL Hornick, M Triggiani, D Radia, C Akin, K Hartmann, J Gotlib, LB Schwartz, S Verstovsek, A Orfao, DD Metcalfe, M Arock, H-P Horny. Refined diagnostic criteria and classification of mast cell leukemia (MCL) and myelomastocytic leukemia (MML): a consensus proposal. Ann Oncol 2014;25(9):1691-700.

  18. RC Johnson, NM Savage, T Chiang, A Cherry, JR Gotlib, DA Arber, TI George. Hidden Mastocytosis in AML with t(8;21). Am J Clin Pathol (in press) (2013).

  19. JM Morgado, O Perbellini, RC Johnson, C Teodósio, A Matito, I Álvarez-Twose, P Bonadonna, A Zamò, M Jara-Acevedo, A Mayado, A Garcia-Montero, M Mollejo, TI George, R Zanotti, A Orfao, L Escribano and L Sánchez-Muñoz. CD30 expression by bone marrow mast cells from different diagnostic variants of systemic mastocytosis. Histopathology (in press) (2013)

  20. J Gotlib, JE Maxson, TI George, JW Tyner. The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatment. Blood 2013 July 29. [Epub ahead of print].

  21. JD Merker, KM Roskin, D Ng, C Pan, DG Fisk, JJ King, R Hoh, LM Okumoto, P Abidi, R Hewitt, CD Jones, MJ Clark, B Zhang, AM Cherry, TI George, JM Cherry, M Snyder, SD Boyd, JL Zehnder, AZ Fire, JR Gotlib. Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and nonrecurrent candidate genes. Haematologica 2013 Jul 19. [Epub ahead of print].

  22. I Pereira, TI George, DA Arber. Atlas of Peripheral Blood. The Primary Diagnostic Tool. Wolters Kluwer, Lippincott Williams and Wilkins, Inc., Philadelphia, PA (2012).

  23. TI George. Malignant or Benign Leukocytosis. Hematology Am Soc Hematol Educ Program. 2012;2012: 475-84.

  24. NM Savage, RC Johnson, J Gotlib, TI George. Myeloid and Lymphoid Neoplasms with FGFR1 Abnormalities. Am JHematol 2013;88:427-430.

  25. P Valent, S Cerny-Reiterer, H Herrmann, I Mirkina, TI George, K Sotlar, WR Sperr, H-P Horny. Phenotypic heterogeneity, novel diagnostic markers, and target expression profiles in normal and neoplastic human mast cells. Best Pract Res Clin Hem 2010; 23:369-78.

  26. AR Arredondo, J Gotlib, L Shier, B Medeiros, K Wong, A Cherry, C Corless, DA Arber, P Valent, TI George. Myelomastocytic leukemia versus mast cell leukemia versus systemic mastocytosis associated with acute myeloid leukemia: a diagnostic challenge. American Journal of Hematology 2010;85(8):600-6.

  27. DP O’Malley, TI George, A Orazi, SL Abbondanzo. Atlas of Nontumor Pathology, First Series, Fascicle 7: Benign and Reactive Conditions of Lymph Node and Spleen. American Registry of Pathology & Armed Forces Institute of Pathology, Washington DC (2009).

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