Mara Steinkamp, Ph.D.

photo of Mara Steinkamp

Research Assistant Professor

Email: MSteinkamp@salud.unm.edu


Interests:

  • Interactions of ErbB receptor tyrosine kinases on the surface of live cells
  • ErbB targeted therapies in ovarian cancer
  • In vivo imaging and two-photon microscopy using fluorescent probes

Education and Certification Information

Post Doctoral Fellowship
Cell Pathology Laboratory, Department of Pathology
University of New Mexico, Albuquerque, New Mexico
2009-2014

Ph.D.
Human Genetics
University of Michigan Medical School
Ann Arbor, MI
2009

B.A.
Biology and English
Williams College
Williamstown, MA
1998


Selected Publications:

  • Kerketta R, Halász ÁM, Steinkamp MP, Wilson BS, Edwards JS. Effect of Spatial Inhomogeneities on the Membrane Surface on Receptor Dimerization and Signal Initiation. Front Cell Dev Biol. 2016 Aug 12;4:81. doi: 10.3389/fcell.2016.00081.PMID:27570763

  • Winner KR, Steinkamp MP, Lee RJ, Swat M, Muller CY, Moses ME, Jiang Y, Wilson BS. Spatial Modeling of Drug Delivery Routes for Treatment of Disseminated Ovarian Cancer. Cancer Res. 2016 Mar 15;76(6):1320-34. doi: 10.1158/0008-5472.CAN-15-1620. PMID:26719526

  • Kanigel Winner K, Steinkamp MP, Lee RJ, Swat M, Muller CY, Moses ME, Jiang Y, Wilson BS. Spatial modeling of drug delivery routes for treatment of disseminated ovarian cancer. Cancer Res. 2015 Dec 30. pii: canres.1620.2015. [Epub ahead of print] PMID:26719526

  • McCabe Pryor M, Steinkamp MP, Halasz AM, Chen Y, Yang S, Smith MS, Zahoransky-Kohalmi G, Swift M, Xu XP, Hanien D, Volkmann N, Lidke DS, Edwards JS, Wilson BS. Orchestration of ErbB3 signaling through heterointeractions and homointeractions. Mol Biol Cell. 2015 Nov 5;26(22):4109-23. doi: 10.1091/mbc.E14-06-1114. Epub 2015 Sep 16. PMID:26378253

  • Valley CC, Arndt-Jovin DJ, Karedla N, Steinkamp MP, Chizhik AI, Hlavacek WS, Wilson BS, Lidke KA, Lidke DS. Enhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancer. Mol Biol Cell. 2015 Nov 5;26(22):4087-99. doi: 10.1091/mbc.E15-05-0269. Epub 2015 Sep 2. PMID:26337388

  • Cleyrat, C., A. Drehshouri, M.P. Steinkamp, M. Vilaine, D. Boassa, M.H. Ellisman, S. Hermouet, and B.S. Wilson, Mpl traffics to the cell surface through conventional and unconventional routes. Traffic, 2014.

  • Davies, S., A. Holmes, L. Lomo, M.P. Steinkamp, H. Kang, C.Y. Muller, and B.S. Wilson, High Incidence of erbB3, erbB4 and met expression in ovarian cancer. Int J Gynecol Pathol, 2014;33:402-10. PMID24901400.

  • Steinkamp, M.P., S.T. Low-Nam, S. Yang, K.A. Lidke, D.S. Lidke, and B.S. Wilson, Erbb3 is an active tyrosine kinase capable of homo- and heterointeractions. Molecular and Cellular Biology, 2014;34:965-977. PMID: 24379439

  • Steinkamp, M.P.*, K.K. Winner*, S. Davies, C. Muller, Y. Zhang, R.M. Hoffman, A. Shirinifard, M. Moses, Y. Jiang, and B.S. Wilson, Ovarian tumor attachment, invasion, and vascularization reflect unique microenvironments in the peritoneum: Insights from xenograft and mathematical models. Front Oncol, 2013;3:97. PMCID:PMC3656359 *shared first author.

  • Girodon, F., M.P. Steinkamp, C. Cleyrat, S. Hermouet, and B.S. Wilson, Confocal imaging studies cast doubt on nuclear localization of jak2v617f. Blood, 2011;118:2633-4. PMID: 21885612

  • Steinkamp, M.P.*, O.A. O'Mahony*, M. Brogley, H. Rehman, E.W. Lapensee, S. Dhanasekaran, M.D. Hofer, R. Kuefer, A. Chinnaiyan, M.A. Rubin, K.J. Pienta, and D.M. Robins, Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy. Cancer Res, 2009;69:4434-42. PMCID: PMC2765801. *shared first author.

  • O'Mahony, O.A.*, M.P. Steinkamp*, M.A. Albertelli, M. Brogley, H. Rehman, and D.M. Robins, Profiling human androgen receptor mutations reveals treatment effects in a mouse model of prostate cancer. Mol Cancer Res, 2008;6:1691-701. PMCID: PMC2748651 *shared first author.

  • Albertelli, M.A., O.A. O'Mahony, M. Brogley, J. Tosoian, M. Steinkamp, S. Daignault, K. Wojno, and D.M. Robins, Glutamine tract length of human androgen receptors affects hormone-dependent and -independent prostate cancer in mice. Hum Mol Genet, 2008;17:98-110. PMID: 17906287

  • Boros, L.G., M.P. Steinkamp, J.C. Fleming, W.N. Lee, M. Cascante, and E.J. Neufeld, Defective rna ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (trma). Blood, 2003;102:3556-61. PMID:12893755

  • Steinkamp, M., A. Geva, S. Joffe, C.N. Lapp, and E.J. Neufeld, Chronic disseminated intravascular coagulation and childhood-onset skin necrosis resulting from homozygosity for a protein c gla domain mutation, arg15trp. J Pediatr Hematol Oncol, 2002;24:685-8. PMID: 12439046

Search PubMed:

Mara P. Steinkamp on PubMed