Cédric Cleyrat, Ph.D.

picture of cedric cleyrat

Research Assistant Professor

Email: ccleyrat@salud.unm.edu
Phone: 505-272-1436


Interests:

  • Myeloproliferative Neoplasms (MPNs)
  • High affinity receptor for IgE (FcεRI)
  • Intracellular trafficking and signaling
  • Genetic engineering

Education and Certification Information

Postdoctoral Fellow
Cell Pathology & Hematology-Oncology
UNM Department of Pathology & UNM Cancer Center
Albuquerque, NM
2011-2014

Ph.D.
Hematology-Oncology
National Institute for Health & Medical Research & Cancer Research Center of Nantes-Angers
University of Nantes, France
2007-2010

Certification to Perform Animal Experiments - Level 1
National Veterinary School of Nantes
France
2010

M.S.
Biology & Organic Chemistry
University of La Rochelle, France

M.S.
Biotechnologies, Bioindustries & Bioprocesses
La Rochelle Institute of Technology
La Rochelle, France
2006

B.S.
Structural Biochemistry
University of La Rochelle, France
2004


Selected Publications:

  • Ponpuak, M., Mandell, M., Kimura, T., Chauhan, S., Cleyrat, C. and Deretic, V. (2015). Secretory autophagy. Current Opinion in Cell Biology (Review article), 35:106-116. Most downloaded article in 2015

  • Klionsky, D.J., Cleyrat, C., et al. (2016). Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (2nd edition). Autophagy Jan 2;12(1):1-222. Most read Autophagy article since 2011

  • Ponpuak, M., Mandell, M., Kimura, T., Chauhan, S., Cleyrat, C. and Deretic, V. (2015) Secretory autophagy. Current Opinion in Cell Biology (Review article), in press.

  • DeVore, M.S., Stich, D.G., Keller, A.M., Ghosh, Y., Goodwin, P.M., Phipps, M.E., Stewart, M.H., Cleyrat, C., Wilson, B.S., Lidke, D.S.,. Hollingsworth, J.A. and Werner, J.H. (2015). Three dimensional time-gated tracking of non-blinking quantum dots in live cells. Proceedings of SPIE, 2015 Mar 12;9338.

  • Cleyrat, C., Darehshouri, A., Steinkamp, M.P., Vilaine, M., Boassa, D., Ellisman, M.H., Hermouet, S. and Wilson, B.S. (2014). Mpl traffics to the cell surface through conventional and unconventional routes. Traffic 15(9): 961-82.

  • Cleyrat, C., Darehshouri, A., Anderson, K. L., Page, C., Lidke, D. S., Volkmann, N., Hanein, D. and Wilson, B. S. (2013). The architectural relationship of components controlling mast cell endocytosis. J Cell Science 126, 4913-25.

  • Carillo, S., Henry, L., Lippert, E., Girodon, F., Guiraud, I., Richard, C., Dubois-Galopin, F., Cleyrat, C., Jourdan, E., Kralovics, R. et al. (2011). Nested high-resolution melting curve analysis a highly sensitive, reliable, and simple method for detection of JAK2 exon 12 mutations--clinical relevance in the monitoring of polycythemia. J Molecular Diagnostics 13, 263-70.

  • *Boissinot, M. & *Cleyrat, C., Vilaine, M., Jacques, Y., Corre, I. and Hermouet, S. (2011). Anti-inflammatory cytokines hepatocyte growth factor and interleukin-11 are over-expressed in Polycythemia Vera and contribute to the growth of clonal erythroblasts independently of JAK2V617F. Oncogene 30, 990-1001.
    *Shared first author

  • Girodon, F., Steinkamp, M. P., Cleyrat, C., Hermouet, S. and Wilson, B. S. (2011). Confocal imaging studies cast doubt on nuclear localization of JAK2V617F. Blood 118, 2633-4.

  • Cleyrat, C., Jelinek, J., Girodon, F., Boissinot, M., Ponge, T., Harousseau, J. L., Issa, J. P. and Hermouet, S. (2010). JAK2 mutation and disease phenotype: a double L611V/V617F in cis mutation of JAK2 is associated with isolated erythrocytosis and increased activation of AKT and ERK1/2. Leukemia 24, 1069-73.

  • Fouassier, M., Girodon, F., Cleyrat, C., Robillard, N., Garand, R. and Hermouet, S. (2009). Absence of JAK2-V617F in paroxysmal nocturnal haemoglobinuria-associated thrombosis. Thromb Haemost 102, 180-2.

  • Girodon, F., Schaeffer, C., Cleyrat, C., Mounier, M., Lafont, I., Santos, F. D., Duval, A., Maynadie, M. and Hermouet, S. (2008). Frequent reduction or absence of detection of the JAK2-mutated clone in JAK2V617F-positive patients within the first years of hydroxyurea therapy. Haematologica 93, 1723-7.

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Cédric Cleyrat on PubMed